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Effects of Vigabatrin, an Irreversible GABA Transaminase Inhibitor, on Ethanol Reinforcement and Ethanol Discriminative Stimuli in Mice

We tested the hypothesis that the irreversible gamma-amino butyric acid (GABA) transaminase inhibitor, γ-vinyl GABA (Vigabatrin; VGB) would reduce ethanol reinforcement and enhance the discriminative stimulus effect of ethanol, effectively reducing ethanol intake. The present studies used adult C57B...

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Detalhes bibliográficos
Main Authors: Griffin, William C., Nguyen, Shaun A., Deleon, Christopher P., Middaugh, Lawrence D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3296837/
https://ncbi.nlm.nih.gov/pubmed/22336593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FBP.0b013e3283512c56
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