Epigallocatechin Gallate Induces Expression of Heme Oxygenase-1 in Endothelial Cells via p38 MAPK and Nrf-2 that Suppresses Pro-inflammatory Actions of TNF-α

Epigallocatechin gallate (EGCG), the major polyphenol in green tea, acutely stimulates production of nitric oxide (NO) from vascular endothelium to reduce hypertension, and improve endothelial dysfunction in SHR rats. Herein, we explored additional mechanisms whereby EGCG may mediate beneficial card...

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Detalhes bibliográficos
Main Authors: Pullikotil, Philomena, Chen, Hui, Muniyappa, Ranganath, Greenberg, Cynthia C., Yang, Shutong, Reiter, Chad E. N., Lee, Ji-Won, Chung, Jay H., Quon, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3296830/
https://ncbi.nlm.nih.gov/pubmed/22137262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jnutbio.2011.06.007
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