Accumulation of argpyrimidine, a methylglyoxal-derived advanced glycation end product, increases apoptosis of lens epithelial cells both in vitro and in vivo

The formation of advanced glycation end products (AGEs) has been considered to be a potential causative factor of injury to lens epithelial cells (LECs). Damage of LECs is believed to contribute to cataract formation. The purpose of this study was to investigate the cytotoxic effect of AGEs on LECs...

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Hlavní autoři: Kim, Junghyun, Kim, Ohn Soon, Kim, Chan-Sik, Sohn, Eunjin, Jo, Kyuhyung, Kim, Jin Sook
Médium: Artigo
Jazyk:Inglês
Vydáno: Korean Society for Biochemistry and Molecular Biology 2012
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3296813/
https://ncbi.nlm.nih.gov/pubmed/22139526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2012.44.2.012
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