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PER3 Polymorphism and Insomnia Severity in Alcohol Dependence

STUDY OBJECTIVES: Insomnia is common, persistent, and associated with relapse in alcohol-dependent (AD) patients. Although the underlying mechanisms are mostly unstudied, AD patients have impaired circadian rhythms and sleep drive, which may be genetically influenced. A polymorphism in the PER3 gene...

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Detalhes bibliográficos
Main Authors: Brower, Kirk J., Wojnar, Marcin, Sliwerska, Elzbieta, Armitage, Roseanne, Burmeister, Margit
Formato: Artigo
Idioma:Inglês
Publicado em: Associated Professional Sleep Societies, LLC 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3296799/
https://ncbi.nlm.nih.gov/pubmed/22467995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5665/sleep.1748
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