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Evaluation of Cervical Mucosa in Transmission Bottleneck during Acute HIV-1 Infection Using a Cervical Tissue-Based Organ Culture

BACKGROUND: Although there are different strains of HIV-1 in a chronically infected individual, only one or limited virus strains are successfully transmitted to a new individual. The reason for this “transmission bottleneck” is as yet unknown. METHODOLOGY/PRINCIPAL FINDINGS: A human cervical explan...

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書誌詳細
主要な著者: Shen, Chengli, Ding, Ming, Ratner, Deena, Montelaro, Ronald C., Chen, Yue, Gupta, Phalguni
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3296723/
https://ncbi.nlm.nih.gov/pubmed/22412886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032539
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