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A Metalloproteinase Secreted by Streptococcus pneumoniae Removes Membrane Mucin MUC16 from the Epithelial Glycocalyx Barrier

The majority of bacterial infections occur across wet-surfaced mucosal epithelia, including those that cover the eye, respiratory tract, gastrointestinal tract and genitourinary tract. The apical surface of all these mucosal epithelia is covered by a heavily glycosylated glycocalyx, a major componen...

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Detalhes bibliográficos
Main Authors: Govindarajan, Bharathi, Menon, Balaraj B., Spurr-Michaud, Sandra, Rastogi, Komal, Gilmore, Michael S., Argüeso, Pablo, Gipson, Ilene K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3296694/
https://ncbi.nlm.nih.gov/pubmed/22412870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032418
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