Xanthine oxidase produces hydrogen peroxide which contributes to reperfusion injury of ischemic, isolated, perfused rat hearts.

Three lines of investigation indicated that hydrogen peroxide (H2O2) from xanthine oxidase (XO) contributes to cardiac dysfunction during reperfusion after ischemia. First, addition of dimethylthiourea (DMTU), a highly permeant O2 metabolite scavenger (but not urea) simultaneously with reperfusion i...

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Détails bibliographiques
Auteurs principaux: Brown, J M, Terada, L S, Grosso, M A, Whitmann, G J, Velasco, S E, Patt, A, Harken, A H, Repine, J E
Format: Artigo
Langue:Inglês
Publié: 1988
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC329662/
https://ncbi.nlm.nih.gov/pubmed/3127425
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