Proposed heparin binding site in antithrombin based on arginine 47. A new variant Rouen-II, 47 Arg to Ser.

Antithrombin Rouen-II, a new inherited variant of antithrombin-III, was found in two members of a family with no definite history of thrombosis. The subjects had normal antigenic concentrations of antithrombin and normal progressive inhibitory activity. However, the variant had defective heparin and...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Borg, J Y, Owen, M C, Soria, C, Soria, J, Caen, J, Carrell, R W
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1988
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329661/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3350974/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113447
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