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Mechanisms whereby exogenous adenine nucleotides improve rabbit renal proximal function during and after anoxia.
When a suspension of rabbit proximal tubules is subjected to anoxia, ATP falls by 80-90% during 40 min of anoxia, and upon reoxygenation (reox) the cells only recover 25-50% of their initial ATP. Addition of Mg-ATP (magnesium chloride-treated ATP), Mg-ADP, or Mg-AMP (five aliquots of 200 nmol/ml add...
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| Publicado no: | J Clin Invest |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
1988
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329657/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3350972/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113443 |
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