Identifying Clinical Improvement in Consolidation Single-arm Phase II Trials in Ovarian Cancer Patients in Second or Greater Clinical Remission

OBJECTIVE: Estimates of Progression-Free Survival (PFS) from single-arm Phase II consolidation/maintenance trials for recurrent ovarian cancer are usually interpreted in the context of historical controls. We illustrate how the duration of second-line therapy (SLT), the time on the investigational t...

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Autori principali: Iasonos, Alexia, Sabbatini, Paul, Spriggs, David R., Aghajanian, Carol A., O’Cearbhaill, Roisin E., Hensley, Martee L., Thaler, Howard T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3296556/
https://ncbi.nlm.nih.gov/pubmed/22080877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/IGC.0b013e31822e29aa
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