Decay-accelerating factor protects human tumor cells from complement-mediated cytotoxicity in vitro.

The disialoganglioside GD2 is expressed on a wide spectrum of human tumor types, including neuroblastomas and melanomas. Upon binding of 3F8, a murine monoclonal antibody (MAb) specific for GD2, neuroblastomas and some melanomas are sensitive to killing by human complement, whereas some melanomas ar...

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Bibliografiske detaljer
Main Authors: Cheung, N K, Walter, E I, Smith-Mensah, W H, Ratnoff, W D, Tykocinski, M L, Medof, M E
Format: Artigo
Sprog:Inglês
Udgivet: 1988
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC329640/
https://ncbi.nlm.nih.gov/pubmed/2450893
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