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Estimating the Distribution of Selection Coefficients from Phylogenetic Data Using Sitewise Mutation-Selection Models

Estimation of the distribution of selection coefficients of mutations is a long-standing issue in molecular evolution. In addition to population-based methods, the distribution can be estimated from DNA sequence data by phylogenetic-based models. Previous models have generally found unimodal distrib...

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Detalhes bibliográficos
Main Authors: Tamuri, Asif U., dos Reis, Mario, Goldstein, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3296245/
https://ncbi.nlm.nih.gov/pubmed/22209901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.111.136432
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