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Relation of mesangial IgA glomerulonephritis to polymorphism of immunoglobulin heavy chain switch region.

We have investigated the switch regions of Ig heavy chain genes of patients with IgA glomerulonephritis (IgA-GN) using restriction fragment length polymorphism (RFLP) analysis. Genomic DNA from patients and controls was digested with the restriction endonuclease Sst I and transferred to nylon membra...

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Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Demaine, A G, Rambausek, M, Knight, J F, Williams, D G, Welsh, K I, Ritz, E
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 1988
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329611/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2892861/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113361
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