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In Silico Optimization of Atrial Fibrillation-Selective Sodium Channel Blocker Pharmacodynamics

Atrial fibrillation (AF) is the most common type of clinical arrhythmia. Currently available anti-AF drugs are limited by only moderate efficacy and an unfavorable safety profile. Thus, there is a recognized need for improved antiarrhythmic agents with actions that are selective for the fibrillating...

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書目詳細資料
Main Authors: Aguilar-Shardonofsky, Martin, Vigmond, Edward J., Nattel, Stanley, Comtois, Philippe
格式: Artigo
語言:Inglês
出版: The Biophysical Society 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3296055/
https://ncbi.nlm.nih.gov/pubmed/22404917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.01.032
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