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Thrombospondin-1 is a novel negative regulator of liver regeneration after partial hepatectomy via TGF-β1 activation in mice
The matricellular protein thrombospondin-1 (TSP-1) is prominently expressed during tissue repair. TSP-1 binds to matrix components, proteases, cytokines, and growth factors and activates intracellular signals via its multiple domains. TSP-1 converts latent transforming growth factor-β1 (TGF-β1) comp...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3295913/ https://ncbi.nlm.nih.gov/pubmed/22105716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.24800 |
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