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Unexpected diversity in Shisa-like proteins suggests the importance of their roles as transmembrane adaptors

The Shisa family of single-transmembrane proteins is characterized by an N-terminal cysteine-rich domain and a proline-rich C-terminal region. Its founding member, Xenopus Shisa, promotes head development by antagonizing Wnt and FGF signaling. Recently, a mouse brain-specific Shisa protein CKAMP44 (...

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Bibliographic Details
Main Authors: Pei, Jimin, Grishin, Nick V.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3295595/
https://ncbi.nlm.nih.gov/pubmed/22120523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2011.11.011
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