Loss of Human Epidermal Growth Factor Receptor 2 (HER2) Expression in Metastatic Sites of HER2-Overexpressing Primary Breast Tumors

PURPOSE: We evaluated whether patients with human epidermal growth factor receptor 2 (HER2) –positive primary breast tumors had metastatic tumors that were HER2 positive (concordant) or HER2 negative (discordant). We then evaluated whether treatment with trastuzumab or chemotherapy before biopsy of...

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Detalhes bibliográficos
Main Authors: Niikura, Naoki, Liu, Jun, Hayashi, Naoki, Mittendorf, Elizabeth A., Gong, Yun, Palla, Shana L., Tokuda, Yutaka, Gonzalez-Angulo, Ana M., Hortobagyi, Gabriel N., Ueno, Naoto T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2012
Assuntos:
Original Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3295557/
https://ncbi.nlm.nih.gov/pubmed/22124109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2010.33.8889
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