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Development of an assay for in vivo human neutrophil elastase activity. Increased elastase activity in patients with alpha 1-proteinase inhibitor deficiency.

Leukocyte extracts contain enzymes that digest fibrinogen and release a fibrinopeptide A-containing fragment. This study was undertaken to identify the responsible proteinase and to characterize the fibrinopeptide A-containing fragment so that it could be used as an index of enzyme activity. Both th...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Weitz, J I, Landman, S L, Crowley, K A, Birken, S, Morgan, F J
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329544/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3487555/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112545
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