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Solution Structure of Kurtoxin: A Gating Modifier Selective for Cav3 Voltage-Gated Ca(2+) Channels
[Image: see text] Kurtoxin is a 63-amino acid polypeptide isolated from the venom of the South African scorpion Parabuthus transvaalicus. It is the first and only peptide ligand known to interact with Cav3 (T-type) voltage-gated Ca(2+) channels with high affinity and to modify the voltage-dependent...
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Auteurs principaux: | , , , , , , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
American Chemical
Society
2012
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Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3295331/ https://ncbi.nlm.nih.gov/pubmed/22329781 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi201633j |
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