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Solution structure of GxTX-1E, a high affinity tarantula toxin interacting with voltage sensors in Kv2.1 potassium channels

GxTX-1E is a neurotoxin recently isolated from Plesiophrictus guangxiensis venom that inhibits the Kv2.1 channel in pancreatic β-cells. The sequence of the toxin is related to previously studied tarantula toxins that interact with the voltage sensors in Kv channels, and GxTX-1E interacts with the Kv...

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Detalhes bibliográficos
Main Authors: Lee, Seungkyu, Milescu, Mirela, Jung, Hyun Ho, Lee, Ju Yeon, Bae, Chan Hyung, Lee, Chul Won, Kim, Ha Hyung, Swartz, Kenton J., Kim, Jae Il
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918519/
https://ncbi.nlm.nih.gov/pubmed/20509680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100246u
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