Withania somnifera reverses Alzheimer's disease pathology by enhancing low-density lipoprotein receptor-related protein in liver

A 30-d course of oral administration of a semipurified extract of the root of Withania somnifera consisting predominantly of withanolides and withanosides reversed behavioral deficits, plaque pathology, accumulation of β-amyloid peptides (Aβ) and oligomers in the brains of middle-aged and old APP/PS...

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Main Authors: Sehgal, Neha, Gupta, Alok, Valli, Rupanagudi Khader, Joshi, Shanker Datt, Mills, Jessica T., Hamel, Edith, Khanna, Pankaj, Jain, Subhash Chand, Thakur, Suman S., Ravindranath, Vijayalakshmi
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2012
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3295277/
https://ncbi.nlm.nih.gov/pubmed/22308347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1112209109
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