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Pancreatic islet expression of chemokine CCL2 suppresses autoimmune diabetes via tolerogenic CD11c(+) CD11b(+) dendritic cells
Development of type 1 diabetes in the nonobese diabetic (NOD) mouse is preceded by an immune cell infiltrate in the pancreatic islets. The exact role of the attracted cells is still poorly understood. Chemokine CCL2/MCP-1 is known to attract CCR2(+) monocytes and dendritic cells (DCs). We have previ...
में बचाया:
| मुख्य लेखकों: | , , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
National Academy of Sciences
2012
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3295274/ https://ncbi.nlm.nih.gov/pubmed/22328150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1115308109 |
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