Inhibition by human thrombomodulin of factor Xa-mediated cleavage of prothrombin.

Human thrombomodulin significantly inhibited the rate of prothrombin conversion to thrombin by Factor Xa in the presence of phospholipid or platelets, calcium, and Factor Va. Sodium dodecyl sulfate polyacrylamide gel electrophoresis of 125I-prothrombin activation revealed that thrombomodulin reduced...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Thompson, E A, Salem, H H
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1986
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329524/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3013935/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112541
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