Cell-Associated Hemolysis Induced by Helicobacter pylori Is Mediated by Phospholipases with Mitogen-Activated Protein Kinase-Activating Properties

Pathogenic Helicobacter pylori strains can selectively activate epithelial mitogen-activated protein kinase (MAPK) signaling pathways linked with disease. We now demonstrate that H. pylori-induced hemolysis is strain specific and is mediated by phospholipases PldA1 and PldD. Inactivation of PldD inh...

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Detalhes bibliográficos
Main Authors: Sitaraman, Ramakrishnan, Israel, Dawn A., Romero-Gallo, Judith, Peek, Richard M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Bacteriology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3295145/
https://ncbi.nlm.nih.gov/pubmed/22205825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.05252-11
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