Detection and Measurement of Fungal Burden in a Guinea Pig Model of Invasive Pulmonary Aspergillosis by Novel Quantitative Nested Real-Time PCR Compared with Galactomannan and (1,3)-β-d-Glucan Detection

We developed and assessed the diagnostic value of a novel quantitative nested real-time (QNRT) PCR assay targeting the internal transcribed spacer region of ribosomal DNA (rDNA) in a guinea pig model of invasive pulmonary aspergillosis. Groups of 5 immunosuppressed animals that were infected using a...

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Bibliografiska uppgifter
Huvudupphovsmän: Lengerova, Martina, Kocmanova, Iva, Racil, Zdenek, Hrncirova, Kristyna, Pospisilova, Sarka, Mayer, Jiri, Najvar, Laura K., Wiederhold, Nathan P., Kirkpatrick, William R., Patterson, Thomas F.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2012
Ämnen:
Mycology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3295131/
https://ncbi.nlm.nih.gov/pubmed/22189110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.05356-11
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