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Chronic Cellular Hyperexcitability in Elderly Epileptic Rats with Spontaneous Seizures Induced by Kainic Acid Status Epilepticus while Young Adults

Emerging data indicate that age-related brain changes alter seizure susceptibility, seizure-associated neurodegeneration, and responsiveness to AEDs. The present study assessed long-term animal survival in the Kainic Acid (KA) model along with in-vivo spontaneous seizure frequency, cellular hyperexc...

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Detalhes bibliográficos
Principais autores: Zhang, Kun, Tolstykh, Gleb P., Sanchez, Russell M., Cavazos, Jose E.
Formato: Artigo
Idioma:Inglês
Publicado em: JKL International LLC 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3295074/
https://ncbi.nlm.nih.gov/pubmed/22396885
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