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snRNA 3′ End Formation Requires Heterodimeric Association of Integrator Subunits

The Integrator Complex is a group of proteins responsible for the endonucleolytic cleavage of primary small nuclear RNA (snRNA) transcripts within the nucleus. Integrator subunits 9 and 11 (IntS9/11) are thought to contain the catalytic activity based on their high sequence similarity to CPSF100 and...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Albrecht, Todd R., Wagner, Eric J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3295014/
https://ncbi.nlm.nih.gov/pubmed/22252320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06511-11
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