RYBP Represses Endogenous Retroviruses and Preimplantation- and Germ Line-Specific Genes in Mouse Embryonic Stem Cells

Polycomb repressive complexes (PRCs) are important chromatin regulators of embryonic stem (ES) cell function. RYBP binds Polycomb H2A monoubiquitin ligases Ring1A and Ring1B and has been suggested to assist PRC localization to their targets. Moreover, constitutive inactivation of RYBP precludes ES c...

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Main Authors: Hisada, Kaori, Sánchez, Carmen, Endo, Takaho A., Endoh, Mitsuhiro, Román-Trufero, Mónica, Sharif, Jafar, Koseki, Haruhiko, Vidal, Miguel
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3295013/
https://ncbi.nlm.nih.gov/pubmed/22269950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06441-11
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