Partial Excision of bla(KPC) from Tn4401 in Carbapenem-Resistant Klebsiella pneumoniae

We describe a novel Tn4401 variant (Tn4401d) in epidemic Klebsiella pneumoniae clone ST258, from which a partial bla(KPC) fragment has been excised along with ISKpn7 and a partial tnpA fragment. Nested-PCR experiments confirmed that this region can be removed from distinct Tn4401 isoforms in both K....

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Autors principals: Chen, Liang, Chavda, Kalyan D., Mediavilla, José R., Jacobs, Michael R., Levi, Michael H., Bonomo, Robert A., Kreiswirth, Barry N.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2012
Matèries:
Mechanisms of Resistance
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3294926/
https://ncbi.nlm.nih.gov/pubmed/22203593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.06182-11
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