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Pharmacodynamic Analysis of a Serine Protease Inhibitor, MK-4519, against Hepatitis C Virus Using a Novel In Vitro Pharmacodynamic System

The development of new antiviral compounds active against hepatitis C virus (HCV) has surged in recent years. In order for these new compounds to be efficacious in humans, optimal dosage regimens for each compound must be elucidated. We have developed a novel in vitro pharmacokinetic/pharmacodynamic...

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Detaylı Bibliyografya
Asıl Yazarlar: Brown, Ashley N., McSharry, James J., Adams, Jonathan R., Kulawy, Robert, Barnard, Richard J. O., Newhard, W., Corbin, A., Hazuda, Daria J., Louie, Arnold, Drusano, George L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3294889/
https://ncbi.nlm.nih.gov/pubmed/22155837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05383-11
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