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Presence of Lamivudine or Emtricitabine Is Associated with Reduced Emergence of Nonnucleoside Reverse Transcriptase Inhibitor Mutations in an Efavirenz-Based Intermittent Antiretroviral Treatment Regimen

Efavirenz concentrations were measured in 21 patients during an interruption cycle of the ANRS 106 Window trial. The median efavirenz concentrations in the patients 12 h, 3 days, and 7 days after discontinuation of the drug were 1,962 ng/ml, 416 ng/ml, and 112 ng/ml, respectively. The half-life rang...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Trancart, Stéphanie, Charreau, Isabelle, Marchou, Bruno, Bocquentin, Muriel, Molina, Jean-Michel, Izopet, Jacques, Tangre, Philippe, Aboulker, Jean-Pierre, Taburet, Anne-Marie
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2012
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3294880/
https://ncbi.nlm.nih.gov/pubmed/22203586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05452-11
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