Single Nucleotide Polymorphisms in the Toll-Like Receptor 3 and CD44 Genes Are Associated with Persistence of Vaccine-Induced Immunity to the Serogroup C Meningococcal Conjugate Vaccine

The rate of decay of antibody concentration following serogroup C meningococcal (MenC) polysaccharide-protein conjugate vaccination varies between individuals. This depends partly on vaccination age but may be influenced by human genetics. We studied 721 single nucleotide polymorphisms (SNPs) across...

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Detalhes bibliográficos
Main Authors: Moore, Catrin E., Hennig, Branwen J., Perrett, Kirsten P., Hoe, J. Claire, Lee, Sue J., Fletcher, Helen, Brocklebank, Denise, O'Connor, Daniel, Snape, Matthew D., Hall, Andrew J., Segal, Shelley, Hill, Adrian V. S., Pollard, Andrew J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3294616/
https://ncbi.nlm.nih.gov/pubmed/22205660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.05379-11
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