Strand specificity for UV-induced DNA repair and mutations in the Chinese hamster HPRT gene.

DNA excision repair modulates the mutagenic effect of many genotoxic agents. The recently observed strand specificity for removal of UV-induced cyclobutane dimers from actively transcribed genes in mammalian cells could influence the nature and distribution of mutations in a particular gene. To inve...

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Detalhes bibliográficos
Main Authors: Vrieling, H, Venema, J, van Rooyen, M L, van Hoffen, A, Menichini, P, Zdzienicka, M Z, Simons, J W, Mullenders, L H, van Zeeland, A A
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC329450/
https://ncbi.nlm.nih.gov/pubmed/1674998
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