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Drug Repositioning and Pharmacophore Identification in the Discovery of Hookworm MIF Inhibitors
The screening of bioactive compound libraries can be an effective approach for repositioning FDA-approved drugs or discovering new pharmacophores. Hookworms are blood-feeding, intestinal nematode parasites that infect up to 600 million people worldwide. Vaccination with recombinant Ancylostoma ceyla...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3294498/ https://ncbi.nlm.nih.gov/pubmed/21944748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2011.07.011 |
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