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A frame-shift mutation in the androgen receptor gene causes complete androgen insensitivity in the testicular-feminized mouse.
The testicular feminized (Tfm) mouse lacks completely androgen responsiveness; and therefore, is unique for studying the role of androgenic steroids in different biological processes. In order to understand the molecular basis of this mutation, 2.8 kilobases of cDNA encoding the Tfm mouse androgen r...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
1991
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC329445/ https://ncbi.nlm.nih.gov/pubmed/2041777 |
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