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Hyperglycemia and Renin-Dependent Hypertension Synergize to Model Diabetic Nephropathy
Rodent models exhibit only the earliest features of human diabetic nephropathy, which limits our ability to investigate new therapies. Hypertension is a prerequisite for advanced diabetic nephropathy in humans, so its rarity in typical rodent models may partly explain their resistance to nephropathy...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
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American Society of Nephrology
2012
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Assuntos: | |
Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3294297/ https://ncbi.nlm.nih.gov/pubmed/22193383 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2011060577 |
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