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GRK2: multiple roles beyond G protein-coupled receptor desensitization
G protein-coupled receptor kinases (GRKs) regulate numerous G protein-coupled receptors (GPCRs) by phosphorylating the intracellular domain of the active receptor, resulting in receptor desensitization and internalization. GRKs also regulate GPCR trafficking in a phosphorylation-independent manner v...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3294176/ https://ncbi.nlm.nih.gov/pubmed/22277298 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2011.12.003 |
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