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Detecting Local Ligand-Binding Site Similarity in Non-Homologous Proteins by Surface Patch Comparison

Functional elucidation of proteins is one of the essential tasks in biology. Function of a protein, specifically, small ligand molecules that bind to a protein, can be predicted by finding similar local surface regions in binding sites of known proteins. Here, we developed an alignment free local su...

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Bibliografische gegevens
Hoofdauteurs: Sael, Lee, Kihara, Daisuke
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3294165/
https://ncbi.nlm.nih.gov/pubmed/22275074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24018
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