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The inhibition of lipopolysaccharide-induced macrophage inflammation by 4 compounds in Hypericum perforatum extract is partially dependent on the activation of SOCS3

Our previous studies found that 4 compounds, namely pseudohypericin, amentoflavone, quercetin, and chlorogenic acid in Hypericum perforatum ethanol extract synergistically inhibited lipopolysaccharide (LPS)-induced macrophage production of prostaglandin E2 (PGE2). Microarray studies led us to hypoth...

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Autors principals: Huang, Nan, Rizshsky, Ludmila, Hauck, Catherine C., Nikolau, Basil J., Murphy, Patricia A., Birt, Diane F.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3294117/
https://ncbi.nlm.nih.gov/pubmed/22245632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phytochem.2011.12.001
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