In Vitro and In Vivo Assessment of Targeting Lipid-based Nanoparticles to the Epidermal Growth Factor-Receptor (EGFR) Using a Novel Heptameric Z(EGFR) Domain

Lipid-based oil-filled nanoparticles (NPs) with a high concentration of surface-chelated nickel (Ni-NPs) were successfully prepared using a Brij78-NTA-Ni conjugate synthesized with Brij 78 (Polyoxyethylene (20) stearyl ether) and nitrilotriacetic acid (NTA). The facile incorporation of the Brij 78-N...

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Main Authors: Benhabbour, S. Rahima, Luft, J. Christopher, Kim, Dongwook, Jain, Anekant, Wadhwa, Saurabh, Parrott, Matthew C., Liu, Rihe, DeSimone, Joseph, Mumper, Russell J.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3294062/
https://ncbi.nlm.nih.gov/pubmed/22037106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2011.10.013
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