A Conserved Mechanism for Bni1- and mDia1-induced Actin Assembly and Dual Regulation of Bni1 by Bud6 and Profilin

Formins have conserved roles in cell polarity and cytokinesis and directly nucleate actin filament assembly through their FH2 domain. Here, we define the active region of the yeast formin Bni1 FH2 domain and show that it dimerizes. Mutations that disrupt dimerization abolish actin assembly activity,...

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Publicat a:	Mol Biol Cell
Autors principals:	Moseley, James B., Sagot, Isabelle, Manning, Amity L., Xu, Yingwu, Eck, Michael J., Pellman, David, Goode, Bruce L.
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Cell Biology 2004
Matèries:	Articles
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329402/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14657240/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E03-08-0621
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