Direct Sorting of the Yeast Uracil Permease to the Endosomal System Is Controlled by Uracil Binding and Rsp5p-dependent Ubiquitylation
The yeast uracil permease, Fur4p, is downregulated by uracil, which is toxic to cells with high permease activity. Uracil promotes cell surface Rsp5p-dependent ubiquitylation of the permease, signaling its endocytosis and further vacuolar degradation. We show here that uracil also triggers the direc...
محفوظ في:
| الحاوية / القاعدة: | Mol Biol Cell |
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| المؤلفون الرئيسيون: | , , , , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
American Society for Cell Biology
2004
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329401/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14657252/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E03-04-0202 |
| الوسوم: |
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