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Reduction in neuronal L-type calcium channel activity in a double knock-in mouse model of Alzheimer’s disease

Increased function of neuronal L-type voltage-sensitive Ca(2+) channels (L-VSCCs) is strongly linked to impaired memory and altered hippocampal synaptic plasticity in aged rats. However, no studies have directly assessed L-VSCC function in any of the common mouse models of Alzheimer’s disease where...

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Detalhes bibliográficos
Main Authors: Thibault, Olivier, Pancani, Tristano, Landfield, Philip W., Norris, Christopher M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293940/
https://ncbi.nlm.nih.gov/pubmed/22265986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2012.01.004
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