Common Genetic Variations in the NALP3 Inflammasome Are Associated with Delayed Apoptosis of Human Neutrophils

BACKGROUND: Neutrophils are key-players in the innate host defense and their programmed cell death and removal are essential for efficient resolution of inflammation. These cells recognize a variety of pathogens, and the NOD-like receptors (NLRs) have been suggested as intracellular sensors of micro...

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Bibliografiske detaljer
Main Authors: Blomgran, Robert, Patcha Brodin, Veronika, Verma, Deepti, Bergström, Ida, Söderkvist, Peter, Sjöwall, Christopher, Eriksson, Per, Lerm, Maria, Stendahl, Olle, Särndahl, Eva
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293864/
https://ncbi.nlm.nih.gov/pubmed/22403613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031326
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