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Genes adopt non-optimal codon usage to generate cell cycle-dependent oscillations in protein levels

The cell cycle is a temporal program that regulates DNA synthesis and cell division. When we compared the codon usage of cell cycle-regulated genes with that of other genes, we discovered that there is a significant preference for non-optimal codons. Moreover, genes encoding proteins that cycle at t...

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Detalhes bibliográficos
Main Authors: Frenkel-Morgenstern, Milana, Danon, Tamar, Christian, Thomas, Igarashi, Takao, Cohen, Lydia, Hou, Ya-Ming, Jensen, Lars Juhl
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293633/
https://ncbi.nlm.nih.gov/pubmed/22373820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2012.3
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