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Ethanol Suppresses Ureagenesis in Rat Hepatocytes: ROLE OF ACETALDEHYDE

We proposed previously that closure of voltage-dependent anion channels (VDAC) in the mitochondrial outer membrane after ethanol exposure leads to suppression of mitochondrial metabolite exchange. Because ureagenesis requires extensive mitochondrial metabolite exchange, we characterized the effect o...

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Détails bibliographiques
Auteurs principaux: Holmuhamedov, Ekhson L., Czerny, Christoph, Beeson, Craig C., Lemasters, John J.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2012
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293599/
https://ncbi.nlm.nih.gov/pubmed/22228763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.293399
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