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Ethanol Suppresses Ureagenesis in Rat Hepatocytes: ROLE OF ACETALDEHYDE

We proposed previously that closure of voltage-dependent anion channels (VDAC) in the mitochondrial outer membrane after ethanol exposure leads to suppression of mitochondrial metabolite exchange. Because ureagenesis requires extensive mitochondrial metabolite exchange, we characterized the effect o...

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Autores principales: Holmuhamedov, Ekhson L., Czerny, Christoph, Beeson, Craig C., Lemasters, John J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293599/
https://ncbi.nlm.nih.gov/pubmed/22228763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.293399
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