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Ubiquitination of Human Leukocyte Antigen (HLA)-DM by Different Membrane-associated RING-CH (MARCH) Protein Family E3 Ligases Targets Different Endocytic Pathways

HLA-DM plays an essential role in the peptide loading of classical class II molecules and is present both at the cell surface and in late endosomal peptide-loading compartments. Trafficking of DM within antigen-presenting cells is complex and is, in part, controlled by a tyrosine-based targeting sig...

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Hlavní autoři: Jahnke, Martin, Trowsdale, John, Kelly, Adrian P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293585/
https://ncbi.nlm.nih.gov/pubmed/22247549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.305961
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