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Characterizing Phospholamban to Sarco(endo)plasmic Reticulum Ca(2+)-ATPase 2a (SERCA2a) Protein Binding Interactions in Human Cardiac Sarcoplasmic Reticulum Vesicles Using Chemical Cross-linking

Chemical cross-linking was used to study protein binding interactions between native phospholamban (PLB) and SERCA2a in sarcoplasmic reticulum (SR) vesicles prepared from normal and failed human hearts. Lys(27) of PLB was cross-linked to the Ca(2+) pump at the cytoplasmic extension of M4 (at or near...

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Detalhes bibliográficos
Main Authors: Akin, Brandy L., Jones, Larry R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293560/
https://ncbi.nlm.nih.gov/pubmed/22247554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.334987
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