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Roles of Hydrophobicity and Charge Distribution of Cationic Antimicrobial Peptides in Peptide-Membrane Interactions

Cationic antimicrobial peptides (CAPs) occur as important innate immunity agents in many organisms, including humans, and offer a viable alternative to conventional antibiotics, as they physically disrupt the bacterial membranes, leading to membrane lysis and eventually cell death. In this work, we...

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Detalhes bibliográficos
Main Authors: Yin, Lois M., Edwards, Michelle A., Li, Jessica, Yip, Christopher M., Deber, Charles M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293554/
https://ncbi.nlm.nih.gov/pubmed/22253439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.303602
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