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Selective Oma1 Protease-mediated Proteolysis of Cox1 Subunit of Cytochrome Oxidase in Assembly Mutants

Stalled biogenesis of the mitochondrial cytochrome c oxidase (CcO) complex results in degradation of subunits containing redox cofactors. The conserved Oma1 metalloproteinase mediates facile Cox1 degradation in cells lacking the Coa2 assembly factor, but not in a series of other mutants stalled in C...

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Détails bibliographiques
Auteurs principaux: Khalimonchuk, Oleh, Jeong, Mi-Young, Watts, Talina, Ferris, Elliott, Winge, Dennis R.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293553/
https://ncbi.nlm.nih.gov/pubmed/22219186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.313148
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